A translational
research
project
What is MediAim
The MediAim project is dedicated to the development of new therapeutic agents and strategies to fight certain serious noncommunicable diseases and selected viral diseases.
Collaboration focuses on experimental, preclinical, translational, and clinical research on the nervous and cardiovascular systems with selected aspects of metabolic research.
Read more about the project >
Research of diseases
Selected publications
Mitochondrial respiration supports autophagy to provide stress resistance during quiescence
Magalhaes-Novais, S., Blecha, J., Naraine, R., Mikesova, J., Abaffy, P., Pecinová, A., Miloševič, M., Bohuslavová, R., Procházka, J., Khan, S., Novotná, E., Šindelka, R., Machan, R., Dewerchin, M., Vlčák, E., Kalucka, J., Štemberková-Hubáčková, S., Benda, A., Goveia, J., Mráček, T., Bařinka, C., Carmeliet, P., Neužil, J., Rohlenová, K., Rohlena, J.
Autophagy. 2022; 2022–03-21(MAR 2022)
NPFFR2-deficient mice fed a high-fat diet develop strong intolerance to glucose
Karnošová, A., Strnadová, V., Železná, B., Kuneš, J., Kašpárek, P., Maletínská, L.
Clinical science. 2023; 137(10); 847–862
Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids
Kysilov, B., Kuchtiak, V., Hrčka Krausová, B., Balík, A., Kořínek, M., Fili, K., Dobrovolski, M., Abramová, V., Chodounská, H., Kudová, E., Božíková, P., Černý, J., Smejkalová, T., Vyklický ml., L.
Cellular and Molecular Life Sciences. 2024, 81(1), 36
