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2023

Potalitsyn, P., Mrázková, L., Selicharová, I., Tencerová, M., Ferenčáková, M., Chrudinová, M., Turnovská, T., Brzozowski, A. M., Marek, A., Kaminský, J., Jiráček, J., Žáková, L. Non-glycosylated IGF2 prohormones are more mitogenic than native IGF2. Communications Biology. 2023, 6, 863

IPHYS

IOCB

Sivčev, S., Kudová, E., Zemková, H. Neurosteroids as positive and negative allosteric modulators of ligand-gated ion channels: P2X receptor perspective. Neuropharmacology. 2023; 234(Aug 15); 109542

IPHYS

IOCB

Piťha, J., Vaněčková, I., Zicha, J. Hypertension after the Menopause: What Can We Learn from Experimental Studies? Physiological Research. 2023, 72(Suppl.2), 91-112

IPHYS

IKEM

Kuneš, J., Hojná, S., Mráziková, L., Montezano, A., Touyz, R. M., Maletínská, L. Obesity, Cardiovascular and Neurodegenerative Diseases: Potential Common Mechanisms. Physiological Research. 2023, 72(Suppl.2), 73-90

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IOCB

Plecitá-Hlavatá, L., Brázdová, A., Křivonosková, M., Hu, Ch.-J., Phang, T., Tauber, J., Li, M., Zhang, H., Hoetzenecker, K., Crnkovic, S., Kwapiszewska, G., Stenmark, K. R. Microenvironmental regulation of T-cells in pulmonary hypertension. Frontiers in Immunology. 2023, 14(Jul 11), 1223122

IPHYS

IOCB

Kortus, Š., Řeháková, K., Klíma, M., Kolcheva, M., Ladislav, M., Langore, E., Baráčková, P., Netolický, J., Misiachna, A., Hemelíková, K., Humpolíčková, J., Chalupská, D., Šilhán, J., Kaniaková, M., Hrčka Krausová, B., Bouřa, E., Zápotocký, M., Horák, M. Subunit-Dependent Surface Mobility and Localization of NMDA Receptors in Hippocampal Neurons Measured Using Nanobody Probes. Journal of Neuroscience. 2023, 43(26), 4755-4774

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IOCB

Freitas-Lima, L. C., Pačesová, A., Staňurová, J., Šácha, P., Marek, A., Hubálek, M., Kuneš, J., Železná, B., Maletínská, L. GPR160 is not a receptor of anorexigenic cocaine- and amphetamine-regulated transcript peptide. European Journal of Pharmacology. 2023; 949(15 June); 175713

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IOCB

Husková, Z., Kikerlová, S., Miklovič, M., Kala, P., Papoušek, F., Neckář, J. Inappropriate activation of the renin-angiotensin system improves cardiac tolerance to ischemia/reperfusion injury in rats with late angiotensin II-dependent hypertension. Frontiers in Physiology. 2023; 14(14 June); 1151308

IPHYS

IKEM

Karnošová, A., Strnadová, V., Železná, B., Kuneš, J., Kašpárek, P., Maletínská, L. NPFFR2-deficient mice fed a high-fat diet develop strong intolerance to glucose. Clinical science. 2023; 137(10); 847-862

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IOCB

Abramová, V., Alvarado, V. L., Hill, M., Smejkalová, T., Malý, M., Valeš, K., Dittert, I., Božíková, P., Kysilov, B., Hrčka Krausová, B., Vyklický, V., Balík, A., Fili, K., Kořínek, M., Chodounská, H., Kudová, E., Číž, D., Martinovič, J., Bartůněk, P., Vyklický ml., L. Effects of Pregnanolone Glutamate and Its Metabolites on GABAA and NMDA Receptors and Zebrafish Behavior. ACS Chemical Neuroscience. 2023; 14(10); 1870-1883

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IOCB

Rehák Bučková, B., Kala, D., Kořenek, J., Matušková, V., Kumpošt, V., Svobodová, L., Otáhal, J., Škoch, A., Šulc, V., Olšerová, A., Vyhnálek, M., Janský, P., Tomek, A., Marusič, P., Jiruška, P., Hlinka, J. Structural connectivity-based predictors of cognitive impairment in stroke patients attributable to aging. PLoS ONE. 2023; 18(4); e0280892

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IKEM

Šilhavý, J., Mlejnek, P., Šimáková, Miroslava, Marková, I., Malínská, H., Hüttl, M., Kazdová, L., Kazantsev, D., Mancini, M., Novotný, J., Pravenec, M. CD36 regulates substrates utilisation in brown adipose tissue of spontaneously hypertensive rats: In vitro study. PLoS ONE. 2023; 18(4); e0283276

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IKEM

Pelantová, H., Tomášová, P., Šedivá, B., Neprašová, B., Mráziková, L., Kuneš, J., Železná, B., Maletínská, L., Kuzma, M. Metabolomic Study of Aging in fa/fa Rats: Multiplatform Urine and Serum Analysis. Metabolites. 2023; 13(4); 552

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IOCB

Hüttl, M., Marková, I., Miklánková, D., Zapletalová, I., Kujal, P., Šilhavý, J., Pravenec, M., Malínská, H. Hypolipidemic and insulin sensitizing effects of salsalate beyond suppressing inflammation in a prediabetic rat model. Frontiers in Pharmacology. 2023; 14(3 Apr); 1117683

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IKEM

Strnadová, V., Karnošová, A., Blechová, M., Neprašová, B., Holá, L., Němcová, A., Myšková, A., Sýkora, D., Železná, B., Kuneš, J., Maletínská, L. Search for lipidized PrRP analogs with strong anorexigenic effect: In vitro and in vivo studies. Neuropeptides. 2023; 98(April); 102319

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IOCB

Habart, D., Koza, A., Leontovyč, I., Kosinová, L., Berková, Z., Kříž, J., Zacharovová, K., Brinkhof, B., Cornelissen, D. J., Magrane, N., Bittenglová, K., Čapek, M., Valečka, J., Habartová, A., Saudek, F. IsletSwipe; a mobile platform for expert opinion exchange on islet graft images. Islets. 2023; 15(1); 2189873

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IKEM

IOCB

Kala, P., Vaňourková, Z., Škaroupková, P., Kompanowska, J., E., Sadowski, J., Walkowska, A., Veselka, J., Táborský, M., Maxová, H., Vaněčková, I., Červenka, L. Endothelin type A receptor blockade increases renoprotection in congestive heart failure combined with chronic kidney disease: Studies in 5/6 nephrectomized rats with aorto-caval fistula. Biomedicine & Pharmacotherapy. 2023; 158(February); 114157

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IKEM

Šilhavý, J., Mlejnek, P., Šimáková, M., Malínská, H., Marková, I., Hüttl, M., Miklánková, D., Kazdová, L., Vrbacký, M., Pecinová, A., Mráček, T., Pravenec, M. Hypolipidemic Effects of Beetroot Juice in SHR-CRP and HHTg Rat Models of Metabolic Syndrome: Analysis of Hepatic Proteome. Metabolites. 2023; 13(2); 192

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IKEM

Mráziková, L., Hojná, S., Vaculová, P., Strnad, Š., Vrkoslav, V., Pelantová, H., Kuzma, M., Železná, B., Kuneš, J., Maletínská, L. Lipidized PrRP Analog Exhibits Strong Anti-Obesity and Antidiabetic Properties in Old WKY Rats with Obesity and Glucose Intolerance. Nutrients. 2023; 15(2); 280

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IOCB

Szczurowska, E., Szánti-Pintér, E., Chetverikov, N., Randáková, A., Kudová, E., Jakubík, J. Modulation of Muscarinic Signalling in the Central Nervous System by Steroid Hormones and Neurosteroids. International Journal of Molecular Sciences. 2023; 24(1); 507

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IOCB

Kolcheva, M., Ladislav, M., Netolický, J., Kortus, Š., Řeháková, K., Hrčka Krausová, B., Hemelíková, K., Misiachna, A., Kádková, A., Klíma, M., Chalupská, D., Horák, M. The pathogenic N650K variant in the GluN1 subunit regulates the trafficking, conductance, and pharmacological properties of NMDA receptors. Neuropharmacology. 2023; 222(1 January); 109297

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IOCB

Kala, P., Gawrys, O., Miklovic, M., Vaňourková, Z., Škaroupková, P., Jíchová, Š., Sadowski, J., Kompanowska, J., E., Walkowska, A., Veselka, J., Táborský, M., Maxová, H., Vaněčková, I., Červenka, L. Endothelin type A receptor blockade attenuates aorto-caval fistula-induced heart failure in rats with angiotensin II-dependent hypertension. Journal of Hypertension. 2023; 41(1); 99-114

IPHYS

IKEM

2022

Holá, L., Železná, B., Karnošová, A., Kuneš, J., Fehrentz, J. A., Denoyelle, S., Cantel, S., Blechová, M., Sýkora, D., Myšková, A., Maletínská, L. A Novel Truncated Liver Enriched Antimicrobial Peptide-2 Palmitoylated at its N-Terminal Antagonizes Effects of Ghrelin. Journal of Pharmacology and Experimental Therapeutics. 2022; 383(2); 129-136

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IOCB

Szczurowska, E., Szánti-Pintér, E., Randáková, A., Jakubík, J., Kudová, E. Allosteric Modulation of Muscarinic Receptors by Cholesterol, Neurosteroids and Neuroactive Steroids. International Journal of Molecular Sciences. 2022; 23(21); 13075

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IOCB

Hojná, S., Kotsaridou, Z., Vaňourková, Z., Rauchová, H., Behuliak, M., Kujal, P., Kadlecová, M., Zicha, J., Vaněčková, I. Empagliflozin Is Not Renoprotective in Non-Diabetic Rat Models of Chronic Kidney Disease. Biomedicines. 2022; 10(10); 2509

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IKEM

Pačesová, A., Holubová, M., Hrubá, L., Strnadová, V., Neprašová, B., Pelantová, H., Kuzma, M., Železná, B., Kuneš, J., Maletínská, L. Age-related metabolic and neurodegenerative changes in SAMP8 mice. Aging. 2022; 14(18); 7300-7327

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IOCB

Malínská, H., Hüttl, M., Marková, I., Miklánková, D., Hojná, S., Papoušek, F., Šilhavý, J., Mlejnek, P., Zicha, J., Hrdlička, J., Pravenec, M., Vaněčková, I. Beneficial Effects of Empagliflozin Are Mediated by Reduced Renal Inflammation and Oxidative Stress in Spontaneously Hypertensive Rats Expressing Human C-Reactive Protein. Biomedicines. 2022; 10(9)); 2066

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IKEM

Mráziková, L., Hojná, S., Pačesová, A., Hrubá, L., Strnadová, V., Neprašová, B., Železná, B., Kuneš, J., Maletínská, L. Palmitoylated prolactin-releasing peptide treatment had neuroprotective but not anti-obesity effect in fa/fa rats with leptin signaling disturbances. Nutrition & Diabetes. 2022; 12(1); 26

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IOCB

Oeckl, J., Janovská, P., Adamcová, K., Bardová, K., Brunner, S., Dieckmann, S., Ecker, J., Fromme, T., Funda, J., Gantert, T., Giansanti, P., Soledad Hidrobo, M., Kuda, O., Kuster, B., Li, Y., Pohl, R., Schmitt, S., Schweizer, S., Zischka, H., Zouhar, P., Kopecký, J., Klingenspor, M. Loss of UCP1 function augments recruitment of futile lipid cycling for thermogenesis in murine brown fat. Molecular Metabolism. 2022; 61(July); 101499

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IOCB

Shapoval, O., Engstová, H., Jirák, D., Drahokoupil, J., Sulková, K., Berková, Z., Pop-Georgievski, O., Holendová, B., Ježek, P., Horák, D. Poly(4-styrenesulfonic acid-co-maleic anhydride)-coated NaGdF4:Yb;Tb;Nd nanoparticles with luminescence and magnetic properties for imaging of pancreatic islets and .beta.-cells. ACS Applied Materials and Interfaces. 2022; 14(16); 18233-18247

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IKEM

Mandal, R., Kohoutová, K., Petrvalská, O., Horváth, M., Srb, P., Veverka, V., Obšilová, V., Obšil, T. FOXO4 interacts with p53 TAD and CRD and inhibits its binding to DNA. Protein Science. 2022; 31(5); e4287

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IOCB

Kysilov, B., Hrčka Krausová, B., Vyklický, V., Smejkalová, T., Kořínek, M., Horák, M., Chodounská, H., Kudová, E., Černý, J., Vyklický ml., L. Pregnane-based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss-of-function disease-associated GRIN mutations. British Journal of Pharmacology. 2022; 179(15); 3970-3990

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IOCB

Senko, A. N., Overall, R. W., Šilhavý, J., Mlejnek, P., Malínská, H., Hüttl, M., Marková, I., Fabel, K. S., Lu, L., Stuchlík, A., Williams, R. W., Pravenec, M., Kempermann, G. Systems genetics in the rat HXB/BXH family identifies Tti2 as a pleiotropic quantitative trait gene for adult hippocampal neurogenesis and serum glucose. PLoS Genetics. 2022; 18(4); e1009638

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IKEM

Chlupáč, J., Matějka, R., Koňařík, M., Novotný, R., Šimůnková, Z., Mrázová, I., Fabian, O., Zapletal, M., Pulda, Z., Lipenský, J. F., Štěpanovská, J., Hanzálek, K., Brož, A., Novák, T., Lodererová, A., Voska, L., Adla, T., Froněk, J., Rozkot, M., Forostyak, S., Kneppo, P., Bačáková, L., Pirk, J. Vascular Remodeling of Clinically Used Patches and Decellularized Pericardial Matrices Recellularized with Autologous or Allogeneic Cells in a Porcine Carotid Artery Model. International Journal of Molecular Sciences. 2022; 23(6); 3310

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IKEM

Magalhaes-Novais, S., Blecha, J., Naraine, R., Mikesova, J., Abaffy, P., Pecinová, A., Miloševič, M., Bohuslavová, R., Procházka, J., Khan, S., Novotná, E., Šindelka, R., Machan, R., Dewerchin, M., Vlčák, E., Kalucka, J., Štemberková-Hubáčková, S., Benda, A., Goveia, J., Mráček, T., Bařinka, C., Carmeliet, P., Neužil, J., Rohlenová, K., Rohlena, J. Mitochondrial respiration supports autophagy to provide stress resistance during quiescence. Autophagy. 2022; 2022-03-21(MAR 2022)

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IKEM

Šilhavý, J., Mlejnek, P., Šimáková, M., Liška, F., Kubovčiak, J., Sticová, E., Pravenec, M. Sodium Accumulation and Blood Capillary Rarefaction in the Skin Predispose Spontaneously Hypertensive Rats to Salt Sensitive Hypertension. Biomedicines. 2022, 10(2), 376

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IKEM

Kudová, E., Mareš, P., Hill, M., Vondráková, K., Tsenov, G., Chodounská, H., Kubová, H., Valeš, K. The Neuroactive Steroid Pregnanolone Glutamate: Anticonvulsant Effect, Metabolites and Its Effect on Neurosteroid Levels in Developing Rat Brains. Pharmaceuticals. 2022, 15(1), 49

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IOCB

Imig, J. D., Červenka, L., Neckář, J. Epoxylipids and soluble epoxide hydrolase in heart diseases. Biochemical Pharmacology. 2022; 195(Jan); 114866

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IKEM

2021

Pravenec, M., Šilhavý, J., Mlejnek, P., Šimáková, M., Mráček, T., Pecinová, A., Tauchmannová, K., Hüttl, M., Malínská, H., Kazdová, L., Neckář, J., Kolář, F., Žurmanová, J., Novotný, J., Houštěk, J. Conplastic strains for identification of retrograde effects of mitochondrial dna variation on cardiometabolic traits in the spontaneously hypertensive rat. Physiological Research. 2021, 70(Suppl.4), S471-S481

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IKEM

Mráziková, L., Neprašová, B., Mengr, A., Popelová, A., Strnadová, V., Holá, L., Železná, B., Kuneš, J., Maletínská, L. Lipidized Prolactin-Releasing Peptide as a New Potential Tool to Treat Obesity and Type 2 Diabetes Mellitus: Preclinical Studies in Rodent Models. Frontiers in Pharmacology. 2021, 12(Nov 18), 779962

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IOCB

Hüttl, M., Marková, I., Miklánková, D., Zapletalová, I., Poruba, M., Haluzík, M., Vaněčková, I., Malínská, H. In a Prediabetic Model, Empagliflozin Improves Hepatic Lipid Metabolism Independently of Obesity and before Onset of Hyperglycemia. International Journal of Molecular Sciences. 2021, 22(21), 11513

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IKEM

Hojná, S., Rauchová, H., Malínská, H., Marková, I., Hüttl, M., Papoušek, F., Behuliak, M., Miklánková, D., Vaňourková, Z., Neckář, J., Kadlecová, M., Kujal, P., Zicha, J., Vaněčková, I. Antihypertensive and metabolic effects of empagliflozin in Ren-2 transgenic rats, an experimental non-diabetic model of hypertension. Biomedicine & Pharmacotherapy. 2021, 144(Dec), 112246

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IKEM

Dolejší, E., Szánti-Pintér, E., Chetverikov, N., Nelic, D., Randáková, A., Doležal, V., Kudová, E., Jakubík, J. Neurosteroids and steroid hormones are allosteric modulators of muscarinic receptor. Neuropharmacology. 2021, 199(Nov 1), 108798

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Mengr, A., Hrubá, L., Exnerová, A., Holubová, M., Popelová, A., Železná, B., Kuneš, J., Maletínská, L. Palmitoylated Prolactin-releasing Peptide Reduced A? Plaques and Microgliosis in the Cerebellum: APP/PS1 Mice Study. Current Alzheimer Research. 2021, 18(8), 607-622

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Krijt, J., Sokolová, J., Šilhavý, J., Mlejnek, P., Kubovčiak, J., Liška, F., Malínská, H., Hüttl, M., Marková, I., Křížková, M., Stipanuk, M. H., Křížek, T., Ditroi, T., Nagy, P., Kožich, V., Pravenec, M. High Cysteine Diet Reduces Insulin Resistance in SHR-CRP Rats. Physiological Research. 2021; 70(5); 687-700

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IKEM

Neckář, J., Alánová, P., Olejníčková, V., Papoušek, F., Hejnová, L., Šilhavý, J., Behuliak, M., Bencze, M., Hrdlička, J., Vecka, M., Jarkovská, D., Švíglerová, J., Mistrová, E., Štengl, M., Novotný, J., Ošťádal, B., Pravenec, M., Kolář, F. Excess ischemic tachyarrhythmias trigger protection infarction in rats. Clinical science. 2021, 135(17), 2143-2163

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IKEM

Pirník, Z., Kořínková, L., Osacká, J., Železná, B., Kuneš, J., Maletínská, L.. Cholecystokinin System Is Involved in the Anorexigenic Effect of Peripherally Applied Palmitoylated Prolactin-Releasing Peptide in Fasted Mice. Physiological Research. 2021, 70(4), 579-590.

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Karnošová, A., Strnadová, V., Holá, L., Železná, B., Kuneš, J., Maletínská, L.. Palmitoylation of Prolactin-Releasing Peptide Increased Affinity for and Activation of the GPR10, NPFF-R2 and NPFF-R1 Receptors: In Vitro Study. International Journal of Molecular Sciences. 2021, 22(16), 8904.

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Dolejší, E., Chetverikov, N., Szánti-Pintér, E., Nelic, D., Randáková, A., Doležal, V., El-Fakahany, E. E., Kudová, E., Jakubík, J. Neuroactive steroids, WIN-compounds and cholesterol share a common binding site on muscarinic acetylcholine receptors. Biochemical Pharmacology. 2021, 192(Oct), 114699

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Holubová, K., Chvojková, M., Hrčka Krausová, B., Vyklický, V., Kudová, E., Chodounská, H., Vyklický ml., L., Valeš, K. Pitfalls of NMDA Receptor Modulation by Neuroactive Steroids. The Effect of Positive and Negative Modulation of NMDA Receptors in an Animal Model of Schizophrenia. Biomolecules. 2021, 11(7), 1026.

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Kacířová, M., Železná, B., Blažková, M., Holubová, M., Popelová, A., Kuneš, J., Šedivá, B., Maletínská, L.. Aging and high-fat diet feeding lead to peripheral insulin resistance and sex-dependent changes in brain of mouse model of tau pathology THY-Tau22. Journal of Neuroinflammation. 2021, 18(1), 141.

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Boušová, K., Bednárová, L., Zouharová, M., Vetýšková, V., Poštulková, K., Hofbauerová, K., Petrvalská, O., Vaněk, O., Tripsianes, K., Vondrášek, J. The order of PDZ3 and TrpCage in fusion chimeras determines their properties—a biophysical characterization. Protein Science. 2021, 30(8), 1653-1666.

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Husková, Z., Kikerlová, S., Sadowski, J., Alánová, P., Sedláková, L., Papoušek, F., Neckář, J. Increased Endogenous Activity of the Renin-Angiotensin System Reduces Infarct Size in the Rats with Early Angiotensin II-dependent Hypertension which Survive the Acute Ischemia/Reperfusion Injury. Frontiers in Pharmacology. 2021, 12(May 28), 679060.

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IKEM

Smejkalová, T., Kořínek, M., Krůšek, J., Hrčka Krausová, B., Candelas Serra, M., Hajduković, D., Kudová, E., Chodounská, H., Vyklický ml., L. Endogenous neurosteroids pregnanolone and pregnanolone sulfate potentiate presynaptic glutamate release through distinct mechanisms. British Journal of Pharmacology. 2021, 178(19), 3888-3904

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Junková, K., Mirchi, L. F., Chylíková, B., Janků, M., Šilhavý, J., Hüttl, M., Marková, I., Miklánková, D., Včelák, J., Malínská, H., Pravenec, M., Šeda, O., Liška, F. Hepatic Transcriptome Profiling Reveals Lack of Acsm3 Expression in Polydactylous Rats with High-Fat Diet-Induced Hypertriglyceridemia and Visceral Fat Accumulation. Nutrients. 2021, 13(5), 1462.

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IKEM

Uchytilová, E., Špicarová, D., Paleček, J. Hypersensitivity Induced by Intrathecal Bradykinin Administration Is Enhanced by N-oleoyldopamine (OLDA) and Prevented by TRPV1 Antagonist. International Journal of Molecular Sciences. 2021, 22(7), 3712.

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IKEM

Pražienková, V., Funda, J., Pirník, Z., Karnošová, A., Hrubá, L., Kořínková, L., Neprašová, B., Janovská, P., Bencze, M., Kadlecová, M., Blahoš, J., Kopecký, J., Železná, B., Kuneš, J., Bardová, K., Maletínská, L. GPR10 gene deletion in mice increases basal neuronal activity, disturbs insulin sensitivity and alters lipid homeostasis. Gene. 2021, 774(Mar 30), 145427

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Hubálková, P., Ladislav, M., Vyklický, V., Smejkalová, T., Hrčka Krausová, B., Kysilov, B., Krůšek, J., Naimová, Ž., Kořínek, M., Chodounská, H., Kudová, E., Černý, J., Vyklický ml., L. Palmitoylation Controls NMDA Receptor Function and Steroid Sensitivity. Journal of Neuroscience. 2021, 41(10), 2119-2134.

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Krausová, A., Burešová, P., Sarnová, L., Oyman-Eyrilmez, G., Škarda, J., Wohl, P., Bajer, L., Sticová, E., Bartoňová, L., Pácha, J., Koubková, G., Procházka, J., Sporrer, M., Durrbeck, C., Stehlíková, Zuzana, V., M., Ziolkowska, N., Sedláček, R., Jirák, D., Kverka, M., Wiche, G., Fabry, B., Kořínek, V., Gregor, M. Plectin ensures intestinal epithelial integrity and protects colon against colitis. Mucosal Immunology. 2021, 14(3), 691-702.

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IKEM

Filová, E., Steinerová, M., Trávníčková, M., Knitlová, J., Musílková, J., Eckhardt, A., Hadraba, D., Matějka, R., Pražák, Š., Štěpanovská, J., Kučerová, J., Riedel, T., Brynda, E., Lodererová, A., Honsová, E., Pirk, J., Koňařík, M., Bačáková, L. Accelerated in vitro recellularization of decellularized porcine pericardium for cardiovascular grafts. Biomedical Materials. 2021, 16(2), 025024.

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IKEM

Honetschlagerová, Z., Gawrys, O., Jíchová, Š., Škaroupková, P., Kikerlová, S., Vaňourková, Z., Husková, Z., Melenovský, V., Kompanowska., Jezierska, E., Sadowski, J., Kolář, F., Novotný, J., Hejnová, L., Kujal, P., Červenka, L. Renal Sympathetic Denervation Attenuates Congestive Heart Failure in Angiotensin II-Dependent Hypertension: Studies with Ren-2 Transgenic Hypertensive Rats with Aortocaval Fistula. Kidney & Blood Pressure Research. 2021, 46(1), 95-113.

IPHYS

IKEM

Ošťádal, B., Ošťádalová, I., Szárszoi, O., Netuka, I., Olejníčková, V., Hlaváčková, M. Sex-dependent effect of perinatal hypoxia on cardiac tolerance to oxygen deprivation in adults. Canadian Journal of Physiology and Pharmacology. 2021, 99(1), 1-8.

IPHYS

IKEM

Brejchová, K., Radner, F. P. W., Balas, L., Palůchová, V., Čajka, T., Chodounská, H., Kudová, E., Schratter, M., Schreiber, R., Durand, T., Zechner, R., Kuda, O. Distinct roles of adipose triglyceride lipase and hormone-sensitive lipase in the catabolism of triacylglycerol estolides. Proceedings of the National Academy of Sciences of the United States of America. 2021, 118(2), e2020999118.

IPHYS

IOCB

2020

Bardová, K., Funda, J., Pohl, R., Čajka, T., Hensler, M., Kuda, O., Janovská, P., Adamcová, K., Irodenko, I., Leňková, L., Zouhar, P., Horáková, O., Flachs, P., Rossmeisl, M., Colca, J., Kopecký, J. Additive Effects of Omega-3 Fatty Acids and Thiazolidinediones in Mice Fed a High-Fat Diet: Triacylglycerol/Fatty Acid Cycling in Adipose Tissue. Nutrients. 2020, 12(12), 3737.

IPHYS

IOCB

Šilhavý, J., Malínská, H., Hüttl, M., Marková, I., Oliyarnyk, O., Mlejnek, P., Šimáková, M., Liška, F., Kazdová, L., Moravcová, R., Novotný, J., Pravenec, M. Downregulation of the Glo1 Gene Is Associated with Reduced Adiposity and Ectopic Fat Accumulation in Spontaneously Hypertensive Rats. ANTIOXIDANTS. 2020, 9(12), 1179.

IPHYS

IKEM

Kořínková, L., Pražienková, V., Černá, L., Karnošová, A., Železná, B., Kuneš, J., Maletínská, L. Pathophysiology of NAFLD and NASH in Experimental Models: The Role of Food Intake Regulating Peptides. Frontiers in Endocrinology. 2020, 11(Nov 26), 597583.

IPHYS

IOCB

Pavlišová, J., Horáková, O., Kalendová, V., Burešová, J., Bardová, K., Holendová, B., Plecitá-Hlavatá, L., Vacková, Š., Windrichová, J., Topolčan, O., Kopecký, J., Rossmeisl, M. Chronic n-3 fatty acid intake enhances insulin response to oral glucose and elevates GLP-1 in high-fat diet-fed obese mice. Food & Function. 2020, 11(11), 9764-9775.

IPHYS

IKEM

Janovská, P., Melenovský, V., Svobodová, M., Havlenová, T., Kratochvílová, H., Haluzík, M., Hošková, E., Pelikánová, T., Kautzner, J., Monzo, L., Jurcová, I., Adamcová, K., Leňková, L., Burešová, J., Rossmeisl, M., Kuda, O., Čajka, T., Kopecký, J. Dysregulation of epicardial adipose tissue in cachexia due to heart failure: the role of natriuretic peptides and cardiolipin. Journal of Cachexia Sarcopenia and Muscle. 2020, 11(6), 1614-1627.

IPHYS

IKEM

Kosek, V., Heczková, M., Novák, F., Meisnerová, E., Nováková, O., Zelenka, J., Bechyňská, K., Vrzáčová, N., Suttnar, J., Hlaváčková, A., Danková, H., Bratová, M., Dasková, N., Malínská, H., Oliyarnyk, O., Wohl, P., Bastová, H., Hajslová, J., Cahová, M. The omega-3 Polyunsaturated Fatty Acids and Oxidative Stress in Long-Term Parenteral Nutrition Dependent Adult Patients: Functional Lipidomics Approach. Nutrients. 2020, 12(8), 2351.

IPHYS

IKEM

Zmeškalová, A., Popelová, A., Exnerová, A., Železná, B., Kuneš, J., Maletínská, L. Cellular Signaling and Anti-Apoptotic Effects of Prolactin-Releasing Peptide and Its Analog on SH-SY5Y Cells. International Journal of Molecular Sciences. 2020, 21(17), 6343.

IPHYS

IOCB

Matějka, R., Koňařík, M., Štěpanovská, J., Lipenský, J., Chlupáč, J., Turek, D., Pražák, Š., Brož, A., Šimůnková, Z., Mrázová, I., Forostyak, S., Kneppo, P., Rosina, J., Bačáková, L., Pirk, J. Bioreactor Processed Stromal Cell Seeding and Cultivation on Decellularized Pericardium Patches for Cardiovascular Use. Applied Sciences-Basel. 2020, 10(16), 5473.

IPHYS

IKEM

Hrčka Krausová, B., Kysilov, B., Černý, J., Vyklický, V., Smejkalová, T., Ladislav, M., Balík, A., Kořínek, M., Chodounská, H., Kudová, E., Vyklický ml., L. Site of Action of Brain Neurosteroid Pregnenolone Sulfate at the N-Methyl-D-Aspartate Receptor. Journal of Neuroscience. 2020, 40(31), 5922-5936.

IPHYS

IOCB

Sivčev, S., Slavíková, B., Ivetic, M., Knězů, M., Kudová, E., Zemková, H. Lithocholic acid inhibits P2X2 and potentiates P2X4 receptor channel gating. Journal of Steroid Biochemistry and Molecular Biology. 2020, 202(Sep), 105725.

IPHYS

IOCB

Mareš, P., Kudová, E., Valeš, K., Kubová, H. Three neurosteroids as well as GABAergic drugs do not convert immediate postictal potentiation to depression in immature rats. Pharmacological Reports. 2020, 72(6), 1573-1578.

IPHYS

IOCB

Smolková, K., Špačková, J., Gotvaldová, K., Dvořák, A., Křenková, A., Hubálek, M., Holendová, B., Vítek, L., Ježek, P. SIRT3 and GCN5L regulation of NADP plus, and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2. Scientific Reports. 2020, 10(1), 8677.

IPHYS

IOCB

Chvojková, M., Rambousek, L., Chodounská, H., Kudová, E., Valeš, K. Synthetic structural modifications of neurosteroid pregnanolone sulfate: Assessment of neuroprotective effects in vivo. European Journal of Pharmacology. 2020, 881(Aug 15), 173187.

IPHYS

IOCB

Strnad, Š., Pražienková, V., Holubová, M., Sýkora, D., Cvačka, J., Maletínská, L., Železná, B., Kuneš, J., Vrkoslav, V. Mass spectrometry imaging of free-floating brain sections detects pathological lipid distribution in a mouse model of Alzheimer's-like pathology. Analyst. 2020, 145(13), 4595-4605.

IPHYS

IOCB

Plecitá-Hlavatá, L., Jabůrek, M., Holendová, B., Tauber, J., Pavluch, V., Berková, Z., Cahová, M., Schröder, K., Brandes, R. P., Siemen, D., Ježek, P. Glucose-Stimulated Insulin Secretion Fundamentally Requires H(2)O(2)Signaling by NADPH Oxidase 4. Diabetes. 2020, 69(7), 1341-1354.

IPHYS

IKEM

Kubánek, M., Schimerová, T., Piherová, L., Brodehl, A., Krebsová, A., Ratnavadivel, S., Stanasiuk, C., Hansíková, H., Zeman, J., Paleček, T., Houštěk, J., Drahota, Z., Nůsková, H., Mikešová, J., Zámečník, J., Macek, M. Jr., Ridzoň, P., Malusková, J., Stránecký, V., Melenovský, V., Milting, H., Kmoch, S. Desminopathy: Novel desmin variants, a new cardiac phenotype, and further evidence for secondary mitochondrial dysfunction. Journal of Clinical Medicine. 2020, 9(4):E937.

IPHYS

IKEM

Filová, E., Staňková, Ľ., Eckhardt, A., Svobodová, J., Musílková, J., Pala, J., Hadraba, D., Brynda, E., Koňařík, M., Pirk, J., Bačáková, L. Modification of Human Pericardium by Chemical Crosslinking. Physiological Research. 2020, 69(1), 49-59.

IPHYS

IKEM

Kacířová, M., Zmeškalová, A., Kořínková, L., Železná, B., Kuneš, J., Maletínská, L. Inflammation: major denominator of obesity, Type 2 diabetes and Alzheimer's disease-like pathology? Clinical science. 2020, 134(5), 547-570.

IPHYS

IOCB

Kořínková, L., Holubová, M., Neprašová, B., Hrubá, L., Pražienková, V., Bencze, M., Haluzík, M., Kuneš, J., Maletínská, L., Železná, B. Synergistic effect of leptin and lipidized PrRP on metabolic pathways in ob/ob mice. Journal of Molecular Endocrinology. 2020, 64(2), 77-90.

IPHYS

IKEM

IOCB

Palůchová, V., Oseeva, M., Březinová, M., Čajka, T., Bardová, K., Adamcová, K., Žáček, P., Brejchová, K., Balas, L., Chodounská, H., Kudová, E., Schreiber, R., Zechner, R., Durand, T., Rossmeisl, M., Abumrad, N. A., Kopecký, J., Kuda, O. Lipokine 5-PAHSA is regulated by adipose triglyceride lipase and primes adipocytes for de novo lipogenesis in mice. Diabetes. 2020, 69(3), 300-312.

IPHYS

IOCB

Sládek, M., Röschová, M., Adámková, V., Hamplová, D., Sumová, A. Chronotype assessment via a large scale socio-demographic survey favours yearlong Standard time over Daylight Saving Time in central Europe. Scientific Reports. 2020, 10(1), 1419.

IPHYS

IKEM

2019

Musílková, J., Filová, E., Pala, J., Matějka, R., Hadraba, D., Vondrášek, D., Kaplan, O., Riedel, T., Brynda, E., Kučerová, J., Koňařík, M., Lopot, F., Pirk, J., Bačáková, L. Human decellularized and crosslinked pericardium coated with bioactive molecular assemblies. Biomedical Materials. 2019, 15(1), 015008.

IPHYS

IKEM

Pšenáková, K., Hexnerová, R., Srb, P., Obšilová, V., Veverka, V., Obšil, T. The redox-active site of thioredoxin is directly involved in apoptosis signal-regulating kinase 1 binding that is modulated by oxidative stress. FEBS Journal. 2019, 287(8), 1626), 1644.

IPHYS

IOCB

Tomášová, P., Bugáňová, M., Pelantová, H., Holubová, M., Šedivá, B., Železná, B., Haluzík, M., Maletínská, L., Kuneš, J., Kuzma, M. Metabolomics Based on MS in Mice with Diet-Induced Obesity and Type 2 Diabetes Mellitus: the Effect of Vildagliptin, Metformin, and Their Combination. Applied Biochemistry and Biotechnology. 2019, 188(1), 165-184.

IPHYS

IKEM

IOCB

Holubová, M., Hrubá, L., Popelová, A., Bencze, M., Pražienková, V., Gengler, S., Kratochvílová, H., Haluzík, M., Železná, B., Kuneš, J., Hölscher, C., Maletínská, L. Liraglutide and a lipidized analog of prolactin-releasing peptide show neuroprotective effects in a mouse model of beta-amyloid pathology. Neuropharmacology. 2019, 144(Jan), 377-387.

IPHYS

IKEM

IOCB

Čermáková, M., Pelantová, H., Neprašová, B., Šedivá, B., Maletínská, L., Kuneš, J., Tomášová, P., Železná, B., Kuzma, M. Metabolomic Study of Obesity and Its Treatment with Palmitoylated Prolactin-Releasing Peptide Analog in Spontaneously Hypertensive and Normotensive Rats. Journal of Proteome Research. 2019, 18(4), 1735-1750.

IPHYS

IOCB

Maletínská, L., Popelová, A., Železná, B., Bencze, M., Kuneš, J. The impact of anorexigenic peptides in experimental models of Alzheimer's disease pathology. Journal of Endocrinology. 2019, 240(2), R47-R72.

IPHYS

IOCB

Pražienková, V., Schirmer, C., Holubová, M., Železná, B., Kuneš, J., Galas, M. C., Maletínská, L. Lipidized Prolactin-Releasing Peptide Agonist Attenuates Hypothermia-Induced Tau Hyperphosphorylation in Neurons. Journal of Alzheimer's Disease. 2019, 67(4), 1187-1200.

IPHYS

IOCB

Pražienková, V., Popelová, A., Kuneš, J., Maletínská, L. Prolactin-Releasing Peptide: Physiological and Pharmacological Properties. International Journal of Molecular Sciences. 2019, 20(21), 5297.

IPHYS

IOCB

Pšenáková, K., Kohoutová, K., Obšilová, V., Ausserlechner, M. J., Veverka, V., Obšil, T. Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics. Cells. 2019, 8(9), 966.

IPHYS

IOCB

Sivčev, S., Slavíková, B., Rupert, M., Ivetic, M., Nekardová, M., Kudová, E., Zemková, H. Synthetic testosterone derivatives modulate rat P2X2 and P2X4 receptor channel gating. Journal of Neurochemistry. 2019, 150(1), 28-43.

IPHYS

IOCB

Šmídová, A., Staňková, K., Petrvalská, O., Lazar, J., Sychrová, H., Obšil, T., Zimmermannová, O., Obšilová, V. The activity of Saccharomyces cerevisiae Na+, K+/H+ antiporter Nha1 is negatively regulated by 14-3-3 protein binding at serine 481. Biochimica Et Biophysica Acta-Molecular Cell Research. 2019, 1866(12), 118534.

IPHYS

IOCB

Šoltésová, M., Elicharová, H., Srb, P., Růžička, M., Janisova, L., Sychrová, H., Lang, J. Nuclear magnetic resonance investigation of water transport through the plasma membrane of various yeast species. FEMS Microbiology Letters. 2019, 366(18), fnz220.

IPHYS

IOCB

Beyrand, V., Voeten, D. F. A. E., Bureš, S., Fernandez, V., Janáček, J., Jirák, D., Rauhut, O., Tafforeau, P. Multiphase progenetic development shaped the brain of flying archosaurs. Scientific Reports. 2019, 9(Jul 25), 10807.

IPHYS

IKEM

Čertíková ,- Chábová, V., Kujal, P., Vaňourková, Z., Škaroupková, P., Sadowski, J., Kompanowska ,, Jezierska, E., Tesař, V., Hammock, B., Imig, J., Maxová, H., Červenka, L., Vaněčková, I. Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats. Kidney & Blood Pressure Research. 2019, 44(6), 1493-1505.

IPHYS

IKEM

Hrdlička, J., Neckář, J., Papoušek, F., Husková, Z., Kikerlová, S., Vaňourková, Z., Vernerová, Z., Akat, F., Vašinová, J., Hammock, B.D., Hwang, S.H., Imig, J. D., Falck, J. R., Červenka, L., Kolář, F. Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats. Frontiers in Pharmacology. 2019, 10(Mar 1), 159.

IPHYS

IKEM

Janáček, J., Jirák, D. Volume tensor estimation using a virtual line grid: study of a developing pheasant brain. Image Analysis and Stereology. 2019, 38(3), 255-260.

IPHYS

IKEM

Janáček, J., Jirák, D. Variance of the isotropic uniform systematic sampling. Image Analysis and Stereology. 2019, 38(3), 261-267.

IPHYS

IKEM

Krátký, V., Kikerlová, S., Husková, Z., Sadowski, J., Kolář, F., Červenka, L. Enhanced Renal Vascular Responsiveness to Angiotensin II and Norepinephrine: A Unique Feature of Female Rats with Congestive Heart Failure. Kidney & Blood Pressure Research. 2019, 44(5), 1128-1141.

IPHYS

IKEM

Neckář, J., Khan, M. A. H., Gross, G. J., Cyprová, M., Hrdlička, J., Kvasilová, A., Falck, J. R., Campbell, W. B., Sedláková, L., Škutová, Š., Olejníčková, V., Gregorovičová, M., Sedmera, D., Kolář, F., Imig, J. D. Epoxyeicosatrienoic acid analog EET-B attenuates post-myocardial infarction remodeling in spontaneously hypertensive rats. Clinical science. 2019, 133(8), 939-951.

IPHYS

IKEM

Řezáčová, L., Hojná, S., Kopkan, L., Rauchová, H., Kadlecová, M., Zicha, J., Vaněčková, I. Role of angiotensin II in chronic blood pressure control of heterozygous Ren-2 transgenic rats: Peripheral vasoconstriction versus central sympathoexcitation. Biomedicine & Pharmacotherapy. 2019, 116(Aug), 108996.

IPHYS

IKEM

Svoboda, P., Křížová, E., Šestáková, Š., Vápenková, K., Knejzlík, Z., Rimpelová, S., Rayová, D., Volfová, N., Křížová, I., Rumlová, M., Sýkora, D., Kizek, R., Haluzík, M., Zídek, V., Zídková, J., Škop, V. Nuclear transport of nicotinamide phosphoribosyltransferase is cell cycle-dependent in mammalian cells, and its inhibition slows cell growth. Journal of Biological Chemistry. 2019, 294(22), 8676-8689.

IPHYS

IKEM

Vacková, Š., Kikerlová, S., Melenovský, V., Kolář, F., Imig, J. D., Kompanowska ,- Jezierska, E., Sadowski, J., Červenka, L. Altered Renal Vascular Responsiveness to Vasoactive Agents in Rats with Angiotensin II-Dependent Hypertension and Congestive Heart Failure. Kidney & Blood Pressure Research. 2019, 44(4), 792-809.

IPHYS

IKEM

Vaněčková, I., Behuliak, M., Hojná, S., Kopkan, L., Kadlecová, M., Zicha, J. Exaggerated blood pressure response to fasudil or nifedipine in hypertensive Ren-2 transgenic rats: role of altered baroreflex. Hypertension Research. 2019, 42(2), 145-154.

IPHYS

IKEM

Vaněčková, I., Hojná, S., Vernerová, Z., Kadlecová, M., Rauchová, H., Kompanowska ,- Jezierska, E., Vaňourková, Z., Červenka, L., Zicha, J. Renoprotection Provided by Additional Diuretic Treatment in Partially Nephrectomized Ren-2 Transgenic Rats Subjected to the Combined RAS and ETA Blockade. Frontiers in physiology. 2019, 10(Sep 18), 1145.

IPHYS

IKEM

Zicha, J., Hojná, S., Kopkan, L., Červenka, L., Vaněčková, I. The Absence of Sympathoexcitation During the Development of Hypertension in Cyp1a1 Ren-2 Transgenic Rats. Physiological Research. 2019, 68(2), 329-334.

IPHYS

IKEM

2018

Popelová, A., Kákonová, A., Hrubá, L., Kuneš, J., Maletínská, L., Železná, B. Potential neuroprotective and anti-apoptotic properties of a long-lasting stable analog of ghrelin: an in vitro study using SH-SY5Y cells. Physiological Research. 2018, 67(2), 339-346.

IPHYS

IOCB

Kapras, V., Vyklický, V., Buděšínský, M., Císařová, I., Vyklický ml., L., Chodounská, H., Jahn, U. Total Synthesis of ent-Pregnanolone Sulfate and Its Biological Investigation at the NMDA Receptor. Organic Letters. 2018, 20(4), 946-949.

IPHYS

IOCB

Krausová, B., Slavíková, B., Nekardová, M., Hubálková, P., Vyklický, V., Chodounská, H., Vyklický ml., L., Kudová, E. Positive Modulators of the N-Methyl-D-aspartate Receptor: Structure-Activity Relationship Study of Steroidal 3-Hemiesters. Journal of Medicinal Chemistry. 2018, 61(10), 4505-4516.

IPHYS

IOCB

Mikulášková, B., Holubová, M., Pražienková, V., Zemenová, J., Hrubá, L., Haluzík, M., Železná, B., Kuneš, J., Maletínská, L. Lipidized prolactin-releasing peptide improved glucose tolerance in metabolic syndrome: Koletsky and spontaneously hypertensive rat study. Nutrition & Diabetes. 2018, 8(Jan 16), 5.

IPHYS

IOCB

Holubová, M., Blechová, M., Kákonová, A., Kuneš, J., Železná, B., Maletínská, L. In Vitro and In Vivo Characterization of Novel Stable Peptidic Ghrelin Analogs: Beneficial Effects in the Settings of Lipopolysaccharide-Induced Anorexia in Mice. Journal of Pharmacology and Experimental Therapeutics. 2018, 366(3), 422-432.

IPHYS

IOCB

Holubová, M., Hrubá, L., Neprašová, B., Majerčíková, Z., Lacinová, Z., Kuneš, J., Maletínská, L., Železná, B. Prolactin-releasing peptide improved leptin hypothalamic signaling in obese mice. Journal of Molecular Endocrinology. 2018, 60(2), 85-94.

IPHYS

IKEM

IOCB

IPHYS

IKEM

IOCB

Adla, S. K., Slavíková, B., Chodounská, H., Vyklický, V., Ladislav, M., Hubálková, P., Krausová, B., Smejkalová, T., Nekardová, M., Šmídková, M., Monincová, L., Souček, R., Vyklický ml., L., Kudová, E. Strong Inhibitory Effect, Low Cytotoxicity and High Plasma Stability of Steroidal Inhibitors of N-Methyl-D-Aspartate Receptors With C-3 Amide Structural Motif. Frontiers in Pharmacology. 2018, 9(Nov 12), 1299.

IPHYS

IOCB

Antošová, Z., Herkommerová, K., Pichová, I., Sychrová, H. Efficient secretion of three fungal laccases from Saccharomyces cerevisiae and their potential for decolorization of textile industry effluent - A comparative study. Biotechnology Progress. 2018, 34(1), 69-80.

IPHYS

IOCB

Boušová, K., Herman, P., Večeř, J., Bednárová, L., Monincová, L., Majer, P., Vyklický ml., L., Vondrášek, J., Teisinger, J. Shared CaM- and S100A1-binding epitopes in the distal TRPM4 N terminus. FEBS Journal. 2018, 285(3), 599-613.

IPHYS

IOCB

Herkommerová, K., Dostál, J., Pichová, I. Decolorization and detoxification of textile wastewaters by recombinant Myceliophthora thermophila and Trametes trogii laccases. 3 Biotech. 2018, 8(12), 505.

IPHYS

IOCB

Jirátová, M., Pospíšilová, A., Rabyk, M., Pařízek, M., Kovář, J., Gálisová, A., Hrubý, M., Jirák, D. Biological characterization of a novel hybrid copolymer carrier system based on glycogen. Drug Delivery and Translational Research. 2018, 8(1), 73-82.

IPHYS

IKEM

Popelová, A., Pražienková, V., Neprašová, B., Kasperová, B. J., Hrubá, L., Holubová, M., Zemenová, J., Blum, D., Železná, B., Galas, M. C., Kuneš, J., Maletínská, L. Novel Lipidized Analog of Prolactin-Releasing Peptide Improves Memory Impairment and Attenuates Hyperphosphorylation of Tau Protein in a Mouse Model of Tauopathy. Journal of Alzheimer's Disease. 2018, 62(4), 1725-1736.

IPHYS

IOCB

Vyklický, V., Krausová, B., Černý, J., Ladislav, M., Smejkalová, T., Kysilov, B., Kořínek, M., Danačíková, Š., Horák, M., Chodounská, H., Kudová, E., Vyklický ml., L. Surface Expression, Function, and Pharmacology of Disease-Associated Mutations in the Membrane Domain of the Human GluN2B Subunit. Frontiers in Molecular Neuroscience. 2018, 11(Apr 6), 110.

IPHYS

IOCB

Červenka, L., Husková, Z., Kopkan, L., Kikerlová, S., Sedláková, L., Vaňourková, Z., Alánová, P., Kolář, F., Hammock, B.D., Hwang, S.H., Imig, J. D., Falck, J. R., Sadowski, J., Kompanowska ,- Jezierska, E., Neckář, J. Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension. Journal of Hypertension. 2018, 36(6), 1326-1341.

IPHYS

IKEM

Dvořák, J., Švihlík, J., Kybic, J., Radochová, B., Janáček, J., Kukal, J., Borovec, J., Habart, D. Volume estimation from single images: an application to pancreatic islets. Image Analysis and Stereology. 2018, 37(3), 191-204.

IPHYS

IKEM

Krátký, V., Kopkan, L., Kikerlová, S., Husková, Z., Táborský, M., Sadowski, J., Kolář, F., Červenka, L. The Role of Renal Vascular Reactivity in the Development of Renal Dysfunction in Compensated and Decompensated Congestive Heart Failure. Kidney & Blood Pressure Research. 2018, 43(6), 1730-1741.

IPHYS

IKEM

IPHYS

IKEM

Neckář, J., Hsu, A., Khan, M. A. H., Gross, G. J., Nithipatikom, K., Cyprová, M., Benák, D., Hlaváčková, M., Sotáková-Kašparová, D., Falck, J. R., Sedmera, D., Kolář, F., Imig, J. D. Infarct size-limiting effect of epoxyeicosatrienoic acid analog EET-B is mediated by hypoxia-inducible factor-1 alpha via downregulation of prolyl hydroxylase 3. American Journal of Physiology-Heart and Circulatory Physiology. 2018, 315(5), H1148-H1158.

IPHYS

IKEM

Peševski, Ž., Kvasilová, A., Stopková, T., Naňka, O., Drobná Krejčí, E., Buffinton, C., Kočková, R., Eckhardt, A., Sedmera, D. Endocardial Fibroelastosis is Secondary to Hemodynamic Alterations in the Chick Embryonic Model of Hypoplastic Left Heart Syndrome. Developmental Dynamics. 2018, 247(3), 509-520.

IPHYS

IKEM

Poledne, R., Zicha, J. Human genome evolution and development of cardiovascular risk factors through natural selection. Physiological Research. 2018, 67(2), 155-163.

IPHYS

IKEM

Pravenec, M., Saba, L. M., Zídek, V., Landa, V., Mlejnek, P., Šilhavý, J., Šimáková, M., Strnad, H., Trnovská, J., Škop, V., Hüttl, M., Marková, I., Oliyarnyk, O., Malínská, H., Kazdová, L., Smith, H., Tabakoff, B. Systems genetic analysis of brown adipose tissue function. Physiological Genomics. 2018, 50(1), 52-66.

IPHYS

IKEM

Rossmeisl, M., Pavlišová, J., Janovská, P., Kuda, O., Bardová, K., Hansíková, J., Svobodová, M., Oseeva, M., Veleba, J., Kopecký Jr., J., Žáček, P., Fišerová, E., Pelikánová, T., Kopecký, J. Differential modulation of white adipose tissue endocannabinoid levels by n-3 fatty acids in obese mice and type 2 diabetic patients. Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids. 2018, 1863(7), 712-725.

IPHYS

IKEM

Sedláková, L., Kikerlová, S., Husková, Z., Červenková, L., Čertíková ,- Chábová, V., Zicha, J., Falck, J. R., Imig, J. D., Kompanowska ,, Jezierska, E., Sadowski, J., Krátký, V., Červenka, L., Kopkan, L. 20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats. Bioscience Reports. 2018, 38(5), BSR20171496.

IPHYS

IKEM

Straka, F., Schorník, D., Mašín, J., Filová, E., Miřejovský, T., Burdíková, Z., Švindrych, Z., Chlup, H., Horný, L., Daniel, M., Machač, J., Skibová, J., Pirk, J., Bačáková, L. A human pericardium biopolymeric scaffold for autologous heart valve tissue engineering: cellular and extracellular matrix structure and biomechanical properties in comparison with a normal aortic heart valve. Journal of Biomaterial Science Polymer Edition. 2018, 29(6), 599-634.

IPHYS

IKEM

Šilhavý, J., Krijt, J., Sokolová, J., Zídek, V., Mlejnek, P., Šimáková, M., Škop, V., Trnovská, J., Oliyarnyk, O., Marková, I., Hüttl, M., Malínská, H., Kazdová, L., Liška, F., Kožich, V., Pravenec, M. Dissecting the role of Folr1 and Folh1 genes in the pathogenesis of metabolic syndrome in spontaneously hypertensive rats. Physiological Research. 2018, 67(4), 657-662.

IPHYS

IKEM

Šilhavý, J., Mlejnek, P., Šimáková, M., Vaněčková, I., Behuliak, M., Kuda, O., Sticová, E., Jirsa, M., Pravenec, M. Acute toxic effects of telmisartan in spontaneously hypertensive rats fed a high fructose diet. Physiological Research. 2018, 67(6), 851-856.

IPHYS

IKEM

Vaněčková, I., Hojná, S., Kadlecová, M., Vernerová, Z., Kopkan, L., Červenka, L., Zicha, J. Renoprotective Effects of ETA Receptor Antagonists Therapy in Experimental Non-Diabetic Chronic Kidney Disease: Is There Still Hope for the Future? Physiological Research. 2018, 67(Suppl.1), S55-S67.

IPHYS

IKEM

2017

Bugáňová, M., Pelantová, H., Holubová, M., Šedivá, B., Maletínská, L., Železná, B., Kuneš, J., Kačer, P., Kuzma, M., Haluzík, M. The effects of liraglutide in mice with diet-induced obesity studied by metabolomics. Journal of Endocrinology. 2017, 233(1), 93-104.

IPHYS

IKEM

IOCB

Pražienková, V., Holubová, M., Pelantová, H., Bugáňová, M., Pirník, Z., Mikulášková, B., Popelová, A., Blechová, M., Haluzík, M., Železná, B., Kuzma, M., Kuneš, J., Maletínská, L. Impact of novel palmitoylated prolactin-releasing peptide analogs on metabolic changes in mice with diet-induced obesity. PLoS ONE. 2017, 12(8), e0183449.

IPHYS

IKEM

IOCB

Adla, S. K., Slavíková, B., Šmídková, M., Tloušťová, E., Svoboda, M., Vyklický, V., Krausová, B., Hubálková, P., Nekardová, M., Holubová, K., Valeš, K., Buděšínský, M., Vyklický ml., L., Chodounská, H., Kudová, E. Physicochemical and biological properties of novel amide-based steroidal inhibitors of NMDA receptors. Steroids. 2017, 117(Jan), 52-61.

IPHYS

IOCB

Gibalová, A., Steinbachová, L., Hafidh, S., Bláhová, V., Gadiou, Z., Michailidis, C., Müller, K., Pleskot, R., Dupľáková, N., Honys, D. Characterization of pollen-expressed bZIP protein interactions and the role of ATbZIP18 in the male gametophyte. Plant Reproduction. 2017, 30(1), 1-17.

IPHYS

IOCB

Kao, H. Y., Dvořák, D., Park, E., Kenney, J., Kelemen, E., Fenton, A.A. Phencyclidine Discoordinates Hippocampal Network Activity But Not Place Fields. Journal of Neuroscience. 2017, 37(49), 12031-12049.

IPHYS

IOCB

Zemenová, J., Sýkora, D., Maletínská, L., Kuneš, J. Lipopeptides as therapeutics: applications and in vivo quantitative analysis. Bioanalysis. 2017, 9(2), 215-230.

IPHYS

IOCB

Jirák, D., Janáček, J. Volume of the crocodilian brain and endocast during ontogeny. PLoS ONE. 2017, 12(6), e0178491.

IPHYS

IKEM

Kostiv, U., Rajsiglová, L., Luptáková, D., Pluháček, T., Vannucci, L., Havlíček, V., Engstová, H., Jirák, D., Šlouf, M., Makovický, P., Sedláček, R., Horák, D. Biodistribution of upconversion/magnetic silica-coated NaGdF4:Yb3+/Er3+ nanoparticles in mouse models. RSC Advances. 2017, 7(73), 45997-46006.

IPHYS

IKEM

Liška, F., Landa, V., Zídek, V., Mlejnek, P., Šilhavý, J., Šimáková, M., Strnad, H., Trnovská, J., Škop, V., Kazdová, L., Starker, C.G., Voytas, D.F., Izsvák, Z., Mancini, M., Šeda, O., Křen, V., Pravenec, M. Downregulation of Plzf Gene Ameliorates Metabolic and Cardiac Traits in the Spontaneously Hypertensive Rat. Hypertension. 2017, 69(6), 1084-1091.

IPHYS

IKEM

Lišková, J., Hadraba, D., Filová, E., Koňařík, M., Pirk, J., Jelen, K., Bačáková, L. Valve interstitial cell culture: Production of mature type I collagen and precise detection. Microscopy Research and Technique. 2017, 80(8), 936-942.

IPHYS

IKEM

Melenovský, V., Petrák, J., Mráček, T., Beneš, J., Borlaug, B. A., Nůsková, H., Pluháček, T., Špatenka, J., Kovalčíková, J., Drahota, Z., Kautzner, J., Pirk, J., Houštěk, J. Myocardial iron content and mitochondrial function in human heart failure: a direct tissue analysis. European Journal of Heart Failure. 2017, 19(4), 522-530.

IPHYS

IKEM

Neckář, J., Svatoňová, A., Weissová, R., Drahota, Z., Zajíčková, P., Brabcová, I., Kolář, D., Alánová, P., Vašinová, J., Šilhavý, J., Hlaváčková, M., Tauchmannová, K., Milerová, M., Ošťádal, B., Červenka, L., Žurmanová, J., Kalous, M., Nováková, O., Novotný, J., Pravenec, M., Kolář, F. Selective replacement of mitochondrial DNA increases the cardioprotective effect of chronic continuous hypoxia in spontaneously hypertensive rats. Clinical science. 2017, 131(9), 865-881.

IPHYS

IKEM

Pravenec, M., Zídek, V., Landa, V., Mlejnek, P., Šilhavý, J., Šimáková, M., Trnovská, J., Škop, V., Marková, I., Malínská, H., Hüttl, M., Kazdová, L., Bardová, K., Tauchmannová, K., Vrbacký, M., Nůsková, H., Mráček, T., Kopecký, J., Houštěk, J. Mutant Wars2 gene in spontaneously hypertensive rats impairs brown adipose tissue function and predisposes to visceral obesity. Physiological Research. 2017, 66(6), 917-924.

IPHYS

IKEM

Sedláková, L., Čertíková ,- Chábová, V., Doleželová, Š., Škaroupková, P., Kopkan, L., Husková, Z., Červenková, L., Kikerlová, S., Vaněčková, I., Sadowski, J., Kompanowska ,, Jezierska, E., Kujal, P., Kramer, H. J., Červenka, L. Renin-angiotensin system blockade alone or combined with ETA receptor blockade: effects on the course of chronic kidney disease in 5/6 nephrectomized Ren-2 transgenic hypertensive rats. Clinical and Experimental Hypertension. 2017, 39(2), 183-195.

IPHYS

IKEM

Straka, F., Schorník, D., Mašín, J., Filová, E., Miřejovský, T., Burdíková, Z., Švindrych, Z., Chlup, H., Horný, L., Veselý, J., Pirk, J., Bačáková, L. A New Approach to Heart Valve Tissue Engineering Based on Modifying Autologous Human Pericardium by 3D Cellular Mechanotransduction. Journal of Biomaterials and Tissue Engineering. 2017, 7(7), 527-543.

IPHYS

IKEM

Šeda, O., Liška, F., Pravenec, M., Vernerová, Z., Kazdová, L., Křenová, D., Zídek, V., Šedová, L., Krupková, M., Křen, V. Connexin 50 Mutation Lowers Blood Pressure in Spontaneously Hypertensive Rat. Physiological Research. 2017, 66(1), 15-28.

IPHYS

IKEM

Špaček, T., Pavluch, V., Alán, L., Capková, N., Engstová, H., Dlasková, A., Berková, Z., Saudek, F., Ježek, P. Nkx6.1 decline accompanies mitochondrial DNA reduction but subtle nucleoid size decrease in pancreatic islet beta-cells of diabetic Goto Kakizaki rats. Scientific Reports. 2017, 7(Nov 15), 15674.

IPHYS

IKEM

Trnovská, J., Šilhavý, J., Kuda, O., Landa, V., Zídek, V., Mlejnek, P., Šimáková, M., Strnad, H., Škop, V., Oliyarnyk, O., Kazdová, L., Haluzík, M., Pravenec, M. Salsalate ameliorates metabolic disturbances by reducing inflammation in spontaneously hypertensive rats expressing human C-reactive protein and by activating brown adipose tissue in nontransgenic controls. PLoS ONE. 2017, 12(6), e0179063.

IPHYS

IKEM

2016

Kuda, O., Březinová, M., Rombaldová, M., Slavíková, B., Pošta, M., Beier, P., Janovská, P., Veleba, J., Kopecký Jr., J., Kudová, E., Pelikánová, T., Kopecký, J. Docosahexaenoic Acid–Derived Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) With Anti-inflammatory Properties. Diabetes. 2016, 65(9), 2580-2590. ISSN 0012-1797.

IPHYS

IKEM

IOCB

Holubová, M., Zemenová, J., Mikulášková, B., Panajotová, V., Stöhr, J., Haluzík, M., Kuneš, J., Železná, B., Maletínská, L. Palmitoylated PrRP analog decreases body weight in DIO rats but not in ZDF rats. Journal of Endocrinology. 2016, 229(2), 85-96.

IPHYS

IOCB

Jirků, M., Lánský, Z., Bednárová, L., Šulc, M., Monincová, L., Majer, P., Vyklický ml., L., Vondrášek, J., Teisinger, J., Boušová, K. The characterization of a novel S100A1 binding site in the N-terminus of TRPM1. International Journal of Biochemistry and Cell Biology. 2016, 78(Sep 2016), 186-193.

IPHYS

IOCB

Kasal, A., Buděšínský, M., Mareš, P., Krištofíková, Z., Leitao, A. J., Sá e Melo, M. L., Silva, M. M. C. Neurosteroids: Can a 2alpha,3alpha-epoxy ring make up for the 3alpha-hydroxyl group? Steroids. 2016, 105(Jan), 12-18.

IPHYS

IOCB

Kuneš, J., Pražienková, V., Popelová, A., Mikulášková, B., Zemenová, J., Maletínská, L. Prolactin-releasing peptide: a new tool for obesity treatment. Journal of Endocrinology. 2016, 230(2), R51-R58.

IPHYS

IOCB

Mikulášková, B., Zemenová, J., Pirník, Z., Pražienková, V., Bednárová, L., Železná, B., Maletínská, L., Kuneš, J. Effect of palmitoylated prolactin-releasing peptide on food intake and neural activation after different routes of peripheral administration in rats. Peptides. 2016, 75(Jan), 109-117.

IPHYS

IOCB

Mikulášková, B., Maletínská, L., Zicha, J., Kuneš, J. The role of food intake regulating peptides in cardiovascular regulation. Molecular and Cellular Endocrinology. 2016, 436(Nov 15), 78-92.

IPHYS

IOCB

Palani, K., Pfeiferová, L., Boušová, K., Bednárová, L., Obšilová, V., Vondrášek, J. Artificial proteins as allosteric modulators of PDZ3 and SH3 in two-domain constructs: A computational characterization of novel chimeric proteins. Proteins-Structure, Function and Bioinformatics. 2016, 84(10), 1358-1374.

IPHYS

IOCB

Pelantová, H., Bugáňová, M., Holubová, M., Šedivá, B., Zemenová, J., Sýkora, D., Kaválková, P., Haluzík, M., Železná, B., Maletínská, L., Kuneš, J., Kuzma, M. Urinary metabolomic profiling in mice with diet-induced obesity and type 2 diabetes mellitus after treatment with metformin, vildagliptin and their combination. Molecular and Cellular Endocrinology. 2016, 431(C), 88-100.

IPHYS

IOCB

Slavíková, B., Chodounská, H., Nekardová, M., Vyklický, V., Ladislav, M., Hubálková, P., Krausová, B., Vyklický ml., L., Kudová, E. Neurosteroid-like Inhibitors of N-Methyl-D-aspartate Receptor: Substituted 2-Sulfates and 2-Hemisuccinates of Perhydrophenanthrene. Journal of Medicinal Chemistry. 2016, 59(10), 4724-4739.

IPHYS

IOCB

Vyklický, V., Smejkalová, T., Krausová, B., Balík, A., Kořínek, M., Borovská, J., Horák, M., Chvojková, M., Kletečková, L., Valeš, K., Černý, J., Nekardová, M., Chodounská, H., Kudová, E., Vyklický ml., L. Preferential Inhibition of Tonically over Phasically Activated NMDA Receptors by Pregnane Derivatives. Journal of Neuroscience. 2016, 36(7), 2161-2175.

IPHYS

IOCB

Jíchová, Š., Kopkan, L., Husková, Z., Doleželová, Š., Neckář, J., Kujal, P., Vernerová, Z., Kramer, H. J., Sadowski, J., Kompanowska ,- Jezierska, E., Reddy, N. R., Falck, J. R., Imig, J. D., Červenka, L. Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats. Journal of Hypertension. 2016, 34(10), 2008-2025.

IPHYS

IKEM

Kočková, R., Kačer, P., Pirk, J., Malý, J., Sukupová, L., Sikula, V., Kotrc, M., Barciaková, L., Honsová, E., Malý, M., Kautzner, J., Sedmera, D., Penicka, M. Native T1 Relaxation Time and Extracellular Volume Fraction as Accurate Markers of Diffuse Myocardial Fibrosis in Heart Valve Disease - Comparison With Targeted Left Ventricular Myocardial Biopsy -. Circulation Journal. 2016, 80(5), 1202-1209.

IPHYS

IKEM

Malínská, H., Oliyarnyk, O., Škop, V., Šilhavý, J., Landa, V., Zídek, V., Mlejnek, P., Šimáková, M., Strnad, H., Kazdová, L., Pravenec, M. Effects of Metformin on Tissue Oxidative and Dicarbonyl Stress in Transgenic Spontaneously Hypertensive Rats Expressing Human C-Reactive Protein. PLoS ONE. 2016, 11(3), e0150924.

IPHYS

IKEM

Pravenec, M., Kožich, V., Krijt, J., Sokolová, J., Zídek, V., Landa, V., Mlejnek, P., Šilhavý, J., Šimáková, M., Škop, V., Trnovská, J., Kazdová, L., Kajiya, T., Wang, J. M., Kurtz, T. W. Genetic Variation in Renal Expression of Folate Receptor 1 (Folr1) Gene Predisposes Spontaneously Hypertensive Rats to Metabolic Syndrome. Hypertension. 2016, 67(2), 335-341.

IPHYS

IKEM

Pravenec, M., Mlejnek, P., Zídek, V., Landa, V., Šimáková, M., Šilhavý, J., Strnad, H., Eigner, S., Eigner-Henke, K., Škop, V., Malínská, H., Trnovská, J., Kazdová, L., Drahota, Z., Mráček, T., Houštěk, J. Autocrine effects of transgenic resistin reduce palmitate and glucose oxidation in brown adipose tissue. Physiological Genomics. 2016, 48(6), 420-427.

IPHYS

IKEM

Rambousek, L., Kletečková, L., Kubesová, A., Jirák, D., Valeš, K., Fritschy, J.M. Rat intra-hippocampal NMDA infusion induces cell-specific damage and changes in expression of NMDA and GABA(A) receptor subunits. Neuropharmacology. 2016, 105(Jun), 594-606.

IPHYS

IKEM

Sedmera, D., Neckář, J., Beneš Jr., J., Pospíšilová, J., Petrák, J., Sedláček, K., Melenovský, V. Changes in Myocardial Composition and Conduction Properties in Rat Heart Failure Model Induced by Chronic Volume Overload. Frontiers in physiology. 2016, 7(Aug 25), 367.

IPHYS

IKEM

Šedová, L., Pravenec, M., Křenová, D., Kazdová, L., Zídek, V., Krupková, M., Liška, F., Křen, V., Šeda, O. Isolation of a Genomic Region Affecting Most Components of Metabolic Syndrome in a Chromosome-16 Congenic Rat Model. PLoS ONE. 2016, 11(3), e0152708. E-ISSN 1932-6203.

IPHYS

IKEM

Škop, V., Trnovská, J., Oliyarnyk, O., Marková, I., Malínská, H., Kazdová, L., Zídek, V., Landa, V., Mlejnek, P., Šimáková, M., Kůdela, M., Pravenec, M., Šilhavý, J. Hepatotoxic effects of fenofibrate in spontaneously hypertensive rats expressing human C-reactive protein. Physiological Research. 2016, 65(6), 891-899.

IPHYS

IKEM

2015

Boušová, K., Jirků, M., Bumba, L., Bednárová, L., Šulc, M., Franěk, M., Vyklický ml., L., Vondrášek, J., Teisinger, J. PIP2 and PIP3 interact with N-terminus region of TRPM4 channel. Biophysical Chemistry. 2015, 205(Oct 2015), 24-32.

IPHYS

IOCB

Jirků, M., Bumba, L., Bednárová, L., Kubala, M., Šulc, M., Franěk, M., Vyklický ml., L., Vondrášek, J., Teisinger, J., Boušová, K. Characterization of the part of N-terminal PIP2 binding site of the TRPM1 channel. Biophysical Chemistry. 2015, 207(Dec), 135-142.

IPHYS

IOCB

Kudová, E., Chodounská, H., Slavíková, B., Buděšínský, M., Nekardová, M., Vyklický, V., Krausová, B., Švehla, P., Vyklický ml., L. A New Class of Potent N-Methyl-D-Aspartate Receptor Inhibitors: Sulfated Neuroactive Steroids with Lipophilic D-Ring Modifications. Journal of Medicinal Chemistry. 2015, 58(15), 5950-5966.

IPHYS

IOCB

Kuneš, J., Vaněčková, I., Mikulášková, B., Behuliak, M., Maletínská, L., Zicha, J. Epigenetics and a new look on metabolic syndrome. Physiological Research. 2015, 64(5), 611-620.

IPHYS

IOCB

Maletínská, L., Nagelová, V., Tichá, A., Zemenová, J., Pirník, Z., Holubová, M., Špolcová, A., Mikulášková, B., Blechová, M., Sýkora, D., Lacinová, Z., Haluzík, M., Železná, B., Kuneš, J. Novel lipidized analogs of prolactin-releasing peptide have prolonged half-lives and exert anti-obesity effects after peripheral administration. International Journal of Obesity. 2015, 39(6), 986-993.

IPHYS

IOCB

Vyklický, V., Krausová, B., Černý, J., Balík, A., Zápotocký, M., Novotný, M., Lichnerová, K., Smejkalová, T., Kaniaková, M., Kořínek, M., Petrovič, M., Kačer, P., Horák, M., Chodounská, H., Vyklický ml., L. Block of NMDA receptor channels by endogenous neurosteroids: implications for the agonist induced conformational states of the channel vestibule. Scientific Reports. 2015, 5(Jun 18), 10935.

IPHYS

IOCB

Alán, L., Olejár, T., Cahová, M., Zelenka, J., Berková, Z., Smětáková, M., Saudek, F., Matěj, R., Ježek, P. Delta Cell Hyperplasia in Adult Goto-Kakizaki (GK/MolTac) Diabetic Rats. Journal of Diabetes Research. 2015, 2015(2015), 385395.

IPHYS

IKEM

Alánová, P., Husková, Z., Kopkan, L., Sporková, A., Jíchová, Š., Neckář, J., Imig, J. D., Klevstig, M., Kolář, F., Reddy, N. R., Falck, J. R., Sadowski, J., Nishiyama, A., Kramer, H. J., Melenovský, V., Červenková, L., Kujal, P., Vernerová, Z., Červenka, L. Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats. Vascular Pharmacology. 2015, 73(Oct 2015), 45-56.

IPHYS

IKEM

Cahová, M., Chrastina, P., Hansíková, H., Drahota, Z., Trnovská, J., Škop, V., Spáčilová, J., Malínská, H., Oliyarnyk, O., Papáčková, Z., Páleníčková, E., Kazdová, L. Carnitine supplementation alleviates lipid metabolism derangements and protects against oxidative stress in non-obese hereditary hypertriglyceridemic rats. Applied Physiology Nutrition and Metabolism-Physiologie appliquee nutrition et metabolisme. 2015, 40(3), 280-291.

IPHYS

IKEM

Cahová, M., Páleníčková, E., Danková, H., Sticová, E., Burian, M., Drahota, Z., Červinková, Z., Kučera, O., Gladkova, C., Stopka, P., Křížová, J., Papáčková, Z., Oliyarnyk, O., Kazdová, L. Metformin prevents ischemia reperfusion-induced oxidative stress in the fatty liver by attenuation of reactive oxygen species formation. American Journal of Physiology-Gastrointestinal and Liver Physiology. 2015, 309(2), G100-G111.

IPHYS

IKEM

Chytilová, A., Borchert, G. H., Mandíková-Alánová, P., Hlaváčková, M., Kopkan, L., Khan, M. A. H., Imig, J. D., Kolář, F., Neckář, J. Tumour necrosis factor-alpha contributes to improved cardiac ischaemic tolerance in rats adapted to chronic continuous hypoxia. Acta Physiologica. 2015, 241(1), 97-108.

IPHYS

IKEM

Jirák, D., Janáček, J., Kear, B. P. A combined MR and CT study for precise quantitative analysis of the avian brain. Scientific Reports. 2015, 5(Oct 30), 16002.

IPHYS

IKEM

Trnovská, J., Šilhavý, J., Zídek, V., Šimáková, M., Mlejnek, P., Landa, V., Eigner, S., Eigner-Henke, K., Škop, V., Oliyarnyk, O., Kazdová, L., Mráček, T., Houštěk, J., Pravenec, M. Gender-related effects on substrate utilization and metabolic adaptation in hairless spontaneously hypertensive rat. Physiological Research. 2015, 64(1), 51-60.

IPHYS

IKEM

Veleba, J., Kopecký Jr., J., Janovská, P., Kuda, O., Horáková, O., Malínská, H., Kazdová, L., Oliyarnyk, O., Škop, V., Trnovská, J., Hájek, M., Škoch, A., Flachs, P., Bardová, K., Rossmeisl, M., Olza, J., de Castro, S. G., Calder, P. C., Gardlo, A., Fišerová, E., Jensen, J., Bryhn, M., Kopecký, J., Pelikánová, T. Combined intervention with pioglitazone and n-3 fatty acids in metformin-treated type 2 diabetic patients: improvement of lipid metabolism. Nutrition & Metabolism. 2015, 12(Dec 2), 52.

IPHYS

IKEM

Sedmera, D., Kočková, R., Vostárek, F., Raddatz, E. Arrhythmias in the developing heart. Acta Physiologica. 2015, 213(2), 303-320.

IPHYS

IKEM